Everything about Nitrone totally explained
A
nitrone is the
N-oxide of an
imine and a
functional group in
organic chemistry. The general structure is R
1R
2C=NR
3+O
- where R
3 is different from H.
A nitrone is
1,3-dipole in
1,3-dipolar cycloadditions. It reacts with
alkenes to an
isoxazolidine:
»
One example of this reaction type is the reaction of various
Baylis-Hillman adducts with
C-Phenyl-N-methylnitrone forming an
isoxazolidine in which R
1 is
phenyl, R
2 is
hydrogen and R
3 is a
methyl group .
Nitrones react with terminal
alkynes and a copper salt to
beta-lactam. This reaction is also called the The
Kinugasa reaction for example in this reaction: :
The first step in this reaction is a dipolar cycloaddition of the nitrone with the
in situ generated
copper(I) acetylide to a 5-membered ring structure which rearranges in the second step.
Further Information
Get more info on 'Nitrone'.
|
External Link Exchanges
Do you know how hard it is to get a link from a large encyclopaedia? Well we're different and will prove it. To get a link from us just add the following HTML to your site on a relevant page:
<a href="http://nitrone.totallyexplained.com">Nitrone Totally Explained</a>
Then simply click through this link from your web page. Our crawlers will verify your link, extract the title of your web page and instantly add a link back to it. If you like you can remove the words Totally Explained and embed the link in article text.
As long as your link remains in place, we'll keep our link to you right here. Please play fair - our crawlers are watching. Your site must be closely related to this one's topic. Any kind of spamming, dubious practises or removing the link will result in your link from us being dropped and, potentially, your whole site being banned. |
